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Each 50 mL, 100 mL and 150 mL. bottle of Cravit i.v. solution for infusion contains 250 mg 500 mg and 750 mg of levofloxacin (5 mg/mL) as active ingredient.
Chemical name: (-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4 methyl-1 piperazinyl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid hemihydrate.
Molecular formula: C18H20FN3O4•½H2O
Molecular weight: 370.38
Melting point: 222-230°C (decomposition).
Light yellowish white to yellowish white crystals or crystalline powder, odorless and bitter taste. Freely soluble in glacial acetic acid, sparingly soluble in water and methanol, slightly soluble in ethanol, and practically insoluble in ether. Light sensitive.
Excipients/Inactive Ingredients: Sodium chloride; sodium hydroxide; hydrochloric acid (q.s. pH 4.8) and water for injection for a volume of 50 mL, 100 mL and 150 mL. The appearance of Cravit i.v. may range from a clear yellow to a greenish-yellow solution.
